id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-280373-xhvhep84	Faust, A.	Challenges and proposed solutions in making clinical research on COVID-19 ethical. A status quo analysis across German research ethics committees	2020-08-14		.txt	text/plain	3663	218	45	Methods: We conducted a qualitative survey across all 52 German RECs on the challenges and potential solutions with reviewing proposals for COVID-19 studies. For the review of these proposals the RECs indicated a broad spectrum of challenges regarding i) social value (e.g. lack of coordination), ii) scientific validity (e.g. provisional study planning), iii) favourable risk-benefit ratio (e.g. difficult benefit assessment), iv) informed consent (e.g. strict isolation measures), v) independent review (e.g. lack of time), vi) fair selection of trial participants (e.g. inclusion of vulnerable groups), and vii) respect for study participants (e.g. data security). The qualitative responses from the 22 RECs on perceived challenges and proposed solutions were all grouped under one or more of seven principles of the employed research ethics framework: social value, scientific validity, informed consent, respect for participants, independent review, favourable risk-benefit analysis and fair participant selection.	./cache/cord-280373-xhvhep84.txt	./txt/cord-280373-xhvhep84.txt