id author title date pages extension mime words sentences flesch summary cache txt cord-280423-v3r7vo0o Desmazes‐Dufeu, Nadine Discordant courses of COVID‐19 in a cohabiting couple of lung transplant recipients 2020-07-31 .txt text/plain 1771 107 52 Solid organ transplant recipients are perceived to be at increased risk of severe COVID‐19 due to their chronic use of immunosuppressive drugs (ISDs) and to their associated conditions. We report here two cases of COVID‐19 in a cohabiting couple of lung transplant recipients for cystic fibrosis, who had different ISDs management and who developed discordant courses of their disease. We report here two cases of synchronic COVID-19 in a cohabiting couple of lung transplant recipients for cystic fibrosis but who had discordant courses of their disease. 13 While lymphopenia and lower CD4 + and CD8 + lymphocytes count have been associated with worst outcome and prolonged viral shedding in the general population of COVID-19 patients, 14 other reports suggested that ISDs per se might diminish the "cytokine storm" underlying the development of acute respiratory distress syndrome (ARDS) and subsequent mortality. ./cache/cord-280423-v3r7vo0o.txt ./txt/cord-280423-v3r7vo0o.txt