id author title date pages extension mime words sentences flesch summary cache txt cord-280628-ok62havd Groß, Sonja SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications 2020-04-30 .txt text/plain 4453 252 43 COVID-19 requires the collaboration of nearly 200 countries to curb the spread of SARS-CoV-2 while gaining time to explore and improve treatment options especially for cardiovascular disease (CVD) and immunocompromised patients, who appear to be at high-risk to die from cardiopulmonary failure. Since the coronavirus disease (COVID19) is still an emerging pandemic with more than 2.1 million confirmed cases worldwide [1] , special focus is currently directed towards the understanding of why people are hospitalized, receive intensive care, and frequently die as a consequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. While higher mortality rates among CVD patients are also associated with other respiratory diseases (especially influenza virus-induced flu or previous SARS epidemics), the question was put forward, whether people treated for heart-related illness are more prone to SARS-CoV-2 viral infection, based on first epidemiological evidence, but particularly based on the presumed upregulation of the SARS-CoV-2 entry receptor. ./cache/cord-280628-ok62havd.txt ./txt/cord-280628-ok62havd.txt