id author title date pages extension mime words sentences flesch summary cache txt cord-281619-fhyamruq Burlacu, Alexandru Unpuzzling COVID-19 Prothrombotic State: Are Preexisting Thrombophilic Risk Profiles Responsible for Heterogenous Thrombotic Events? 2020-08-25 .txt text/plain 2016 112 32 1 The similarity between these 2 conditions is sustained by autopsy studies findings, documented immune pathogenesis, and microcirculation dysfunctions, the ability of SARS-CoV-2 to disseminate the infection in other organs and by the fact that many critically ill COVID-19 patients developed clinical symptoms of shock following a process called "viral sepsis." 2 A recent paper dealing with SARS-CoV-2 and "viral sepsis" raised alarm signals that despite the huge percentage of 71,4% of non-survivors of COVID-19 who matched the grade of overt disseminated intravascular coagulation, the concrete mechanisms of vascular thrombosis are not yet known. The hypercoagulation state consequent to SARS-COV-2 infection seems to manifest not only as pulmonary embolism, but also as other thrombotic events such as deep vein thrombosis, myocardial infarction, or ischemic stroke, 31 suggesting that the most plausible explanation has to be a pattern concerning either the patients or the virus. ./cache/cord-281619-fhyamruq.txt ./txt/cord-281619-fhyamruq.txt