id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-282416-5x3lyuuf	Adams, Hugo J.A.	Chest CT imaging signature of COVID-19 infection: in pursuit of the scientific evidence	2020-06-25		.txt	text/plain	4156	250	51	Original studies which reported the prevalence of chest CT findings in patients with RT-PCR or gene sequencing proven COVID-19 were eligible for inclusion. For each included study, publication date, country of origin, study design (retrospective or prospective), number, gender and age of included patients, inclusion criteria, number of symptomatic patients, duration of symptoms before chest CT, disease severity (based on reported descriptive data), chest CT interpreters, and time interval between chest CT and RT-PCR/gene sequencing, were extracted. For each included study, the frequency of chest CT findings (i.e., normal findings and all individually reported lung abnormalities according to the glossary of terms for thoracic imaging of the Fleischner Society 12 on a patient level) were extracted. Because of the potential of chest CT in adjunct to clinical examination and RT-PCR for the diagnosis of COVID-19, and the rapid proliferation of studies on this topic, a systematic review and meta-analysis was performed to assess the methodological quality of these studies and to determine the frequency of different chest CT findings that are found in this disease.	./cache/cord-282416-5x3lyuuf.txt	./txt/cord-282416-5x3lyuuf.txt