id author title date pages extension mime words sentences flesch summary cache txt cord-282460-z7g3uikr Guillo, Enora COVID-19 pneumonia: Diagnostic and prognostic role of CT based on a retrospective analysis of 214 consecutive patients from Paris, France 2020-08-08 .txt text/plain 2484 125 51 Sensitivity, specificity, negative and positive predictive values of first and expert readings were calculated together with inter reader agreement, with results of RT-PCR as standard of reference and according to symptoms and onset date. Thus, the purpose of our study was to evaluate the diagnostic and prognostic performance of CT in patients referred for COVID-19 suspicion to a French university hospital, depending on symptoms and date of onset, as well as factors associated to poor outcomes in our specific population. In the present study, we found strong inter reader agreement between initial and expert reading for the diagnosis of COVID-19 pneumonia and a sensitivity reaching 93% for expert reading when CT was performed after 5 days of symptoms, considering RT-PCR positivity only as standard of reference. Other studies have used a different reference standard to confirm SARS-Cov-2 infection, not exclusively relying on RT-PCR results but also on a clinical validation based on the combination of symptoms, exposure, and presence of lung imaging features consistent with coronavirus pneumonia [11] . ./cache/cord-282460-z7g3uikr.txt ./txt/cord-282460-z7g3uikr.txt