id author title date pages extension mime words sentences flesch summary cache txt cord-282504-m3npy0om Kastritis, Efstathios Challenges in the Management of patients with systemic light chain (AL) amyloidosis during the COVID‐19 pandemic 2020-06-01 .txt text/plain 4642 217 44 Patients with light chain (AL) amyloidosis have an underlying usually low-grade plasma or B-cell malignancy causing their disease, and they receive chemotherapy (Merlini, et al 2018) , thus, being at higher risk for infections (Kristinsson, et al 2012) , including from SARS-CoV-2, and probably at higher risk for severe COVID-19 (Pietrantonio and Garassino 2020) . Treatments for AL amyloidosis have not been developed in the context of multiple randomized studies, thus, we have limited data to propose one therapy over the other or assess the importance of full vs reduced dosing of critical drugs such as bortezomib or For selected patients who have achieved a satisfactory hematologic response (for example CR or VGPR or even PR with organ response), the treating physician may discuss to complete therapy earlier or continue with a less intensive schedule (for example reduce weekly to bi-weekly bortezomib). ./cache/cord-282504-m3npy0om.txt ./txt/cord-282504-m3npy0om.txt