id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-284257-zplfyqqi	Mocco, J	In Reply: May Cooler Heads Prevail During a Pandemic: Stroke in COVID-19 Patients or COVID-19 in Stroke Patients?	2020-08-28		.txt	text/plain	2341	138	52	Our report, as accepted and published in the NEJM, is a factual account of our observation of a higher than usual number of young patients with large vessel stroke presenting during the peak of the COVID-19 in New York City. To help clarify the scientific and factual inaccuracies as presented by Drs Spiotta and Alawieh, we provide the following brief responses to the statements made in their letter 1 : 1) "Systemic inflammation that may occur after severe COVID-19 infection promotes a prothrombotic state that may predispose to thrombotic events, including stroke. In fact, data is also published specifically addressing macrothrombosis in the internal carotid artery in mild COVID patients, 14, 15 with stroke as a presenting symptom of the disease, 4 newly presenting emergent large vessel occlusions with COVID-19 being a very different population compared to typical ELVO patients 16 and demonstrating that COVID-19 is associated with a 7.6 fold increased odds of suffering stroke as compared to influenza (a similar respiratory virus previously demonstrated to be associated with stroke).	./cache/cord-284257-zplfyqqi.txt	./txt/cord-284257-zplfyqqi.txt