id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-284910-vjcrhwqz	Kirresh, Ali	COVID-19 infection and high intracoronary thrombus burden	2020-07-30		.txt	text/plain	1773	88	38	Emerging evidence demonstrates a strong association with a pro-thrombotic state and we present the first patient admitted with COVID-19 and an inferior ST-segment elevation myocardial infarction (STEMI) with evidence of high intracoronary thrombus burden. We review the mechanism of the high thrombus burden, which may be driven by the significant cytokine storm, endothelial dysfunction, increase risk of coronary plaque rupture and hypercoagulability. We present the first patient admitted with inferior ST-segment elevation myocardial infarction (STEMI) with evidence of high intracoronary thrombus burden and provide a review of potential underlying mechanisms. There are emerging theories regarding the mechanism of increased thrombus burden seen in COVID-19, central to which seems to be a significant proinflammatory state (8). Plaque rupture results in an increase in tissue factor (TF), collagen and platelet activation causing increased fibrin production and a higher thrombus burden (16) .	./cache/cord-284910-vjcrhwqz.txt	./txt/cord-284910-vjcrhwqz.txt