id author title date pages extension mime words sentences flesch summary cache txt cord-285574-i0dh1u5i Ferini-Strambi, Luigi COVID-19 and neurological disorders: are neurodegenerative or neuroimmunological diseases more vulnerable? 2020-07-21 .txt text/plain 6800 310 38 The main goal of this viewpoint review is to assess the vulnerability to SARS-CoV-2 infection and development of COVID-19 among neurological disorders with different pathogenesis and age-related targets such as neurodegenerative vs neuroimmunological diseases. Since SARS-CoV-2 effects on neurodegenerative, as well as neuroimmune diseases, might vary across the different pathogenesis and clinical features, we consider the evidence within three sections: (i) vulnerability to the infection; (ii) modification of the clinical course of disease, in relation to clinical neurological manifestations, disease progression and innovative strategies, to support clinicians in the management of the disease; (iii) trigger for future neurodegeneration. Taken together, these findings suggest that although PD patients may represent a particularly vulnerable population for age-related target, respiratory muscle rigidity related to the disease, and presence of several comorbidities, PD by itself do not appears increase the risk of being infected by SARS-CoV-2 and developing COVID-19 ( Fig. 1) . ./cache/cord-285574-i0dh1u5i.txt ./txt/cord-285574-i0dh1u5i.txt