id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290938-v7giuq53	Ochoa-Callejero, L.	Circulating levels of calcitonin gene-related peptide (CGRP) are lower in COVID-19 patients	2020-10-02		.txt	text/plain	3189	227	54	title: Circulating levels of calcitonin gene-related peptide (CGRP) are lower in COVID-19 patients Background: To better understand the biology of COVID-19, we have explored the behavior of calcitonin gene-related peptide (CGRP), an angiogenic, vasodilating, and immune modulating peptide, in SARS-CoV-2 positive patients. Results: CGRP levels greatly decreased in COVID-19 patients (p<0.001) when compared to controls, and there were no significant differences due to disease severity, sex, age, or comorbidities. When separated by disease severity, the three COVID-19 groups displayed significantly lower levels of CGRP when compared to healthy controls, but there were no significant differences among disease groups (Fig. 1A) . This result may explain the higher expression of RAMP1 that was found in COVID-19 lung samples using multiplex gene expression analysis 6 is the author/funder, who has granted medRxiv a license to display the preprint in (which was not certified by peer review) preprint	./cache/cord-290938-v7giuq53.txt	./txt/cord-290938-v7giuq53.txt