id author title date pages extension mime words sentences flesch summary cache txt cord-290955-m2igkcxv Asli, Rosmonaliza Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with Novel Coronavirus Disease (COVID-19) Treated with Hydroxychloroquine 2020-05-07 .txt text/plain 1388 90 49 title: Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with Novel Coronavirus Disease (COVID-19) Treated with Hydroxychloroquine We report the case of a 60-year-old woman without any cardiac history who developed right bundle brunch block and critically prolonged corrected electrocardiographic QT interval (QTc 631 ms) after treatment for 3 days with HCQ, which resolved on discontinuation of the medication. 1 Currently, there is no proven effective treatment, and medications proposed to inhibit the virus life cycle such as hydroxychloroquine (HCQ), chloroquine, lopinavir/ritonavir, and remdesivir are used off label. An electrocardiograph (ECG) on hospital day 4 (before initiation of HCQ) was normal, with a corrected QT interval (QTc) of 397 ms. On the seventh day of hospitalization, repeat ECG before the morning dose of HCQ showed a new right bundle branch block (RBBB) and critically prolonged QTc (631 ms) ( Figure 2 ). Lopinavir/ritonavir is also associated with the prolongation of QTc, but the ECG after starting this medication was normal. ./cache/cord-290955-m2igkcxv.txt ./txt/cord-290955-m2igkcxv.txt