id author title date pages extension mime words sentences flesch summary cache txt cord-291188-ddw6ir08 Kip, K. E. Temporal Changes in Clinical Practice with COVID-19 Hospitalized Patients: Potential Explanations for Better In-Hospital Outcomes 2020-09-29 .txt text/plain 3452 210 46 Our observed practice pattern of more frequent use of steroids is also consistent with a recently published (September 2, 2020) meta-analysis of six trials involving random assignment of different steroids (dexamethasone, hydrocortisone, methylprednisolone) compared to placebo, and approximately 30% lower risk of 28-day mortality among patients treated with steroids. An obvious question that arises from the present analysis is to what extent did the recent changes in clinical practice (e.g. greater use and earlier initiation of steroids and anticoagulants) lead to overall lower rates of mechanical ventilation and hospital mortality, as well shorter length of hospital stay? Recently treated hospitalized COVID-19 patients in our large health care system have overall lower rates of mechanical ventilation/in-hospital mortality and shorter length of hospital stay compared to earlier intervals. ./cache/cord-291188-ddw6ir08.txt ./txt/cord-291188-ddw6ir08.txt