id author title date pages extension mime words sentences flesch summary cache txt cord-292274-upwn9o2m Ghaffari, Abdi COVID-19 Serological Tests: How Well Do They Actually Perform? 2020-07-04 .txt text/plain 4648 244 44 While IgM and IgG antibodies have been the leading candidates in COVID-19 serological test development, recent studies show that IgA, predominately present in the mucosal tissue, may also play a critical role in the immune response and disease progression [12] . While IgM and IgG antibodies have been the leading candidates in COVID-19 serological test development, recent studies show that IgA, predominately present in the mucosal tissue, may also play a critical role in the immune response and disease progression [12] . Typically, RDT test strips use a drop of blood to detect the presence of patient antibodies (IgG, IgM, or IgA) produced against a specific SARS-CoV-2 antigen ( Figure 2 ). Critics point to gaps in our understanding of immune response to COVID-19 infection, including the ability of serological tests to detect neutralizing antibodies and the capacity of the immune system to provide long-term immunity against SARS-CoV-2. ./cache/cord-292274-upwn9o2m.txt ./txt/cord-292274-upwn9o2m.txt