id author title date pages extension mime words sentences flesch summary cache txt cord-292345-zc209dfx Carroll, Elizabeth Catastrophic Intracranial Hemorrhage in Two Critically Ill Patients with COVID-19 2020-05-26 .txt text/plain 1580 90 51 Although it has been noted that COVID-19 may increase risk for acute cerebrovascular events, including both ischemic and hemorrhagic stroke [2] , to our knowledge, this is the first report of patients with COVID-19 who had catastrophic intracranial hemorrhages. To address this, Thachil noted that use of anticoagulation in patients with elevated D-dimers may decrease mortality by both preventing thrombi and dampening the inflammatory response triggered by COVID-19 [7] . Thus, at our center, it was decided that therapeutic anticoagulation should be initiated empirically for patients with COVID-19 who have a D-dimer > 10,000 ng/ mL and considered for patients who have a D-dimer between 2000 and < 10,000 ng/mL using treatment dose enoxaparin or heparin titrated to a low therapeutic anti-Xa goal of 0.3-0.5 U/mL. ./cache/cord-292345-zc209dfx.txt ./txt/cord-292345-zc209dfx.txt