id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-292997-xbomgwzx	Singh, Sandeep	Takotsubo Syndrome in Patients with COVID-19: a Systematic Review of Published Cases	2020-10-06		.txt	text/plain	2425	140	51	We performed a systematic literature search using PubMed/Medline, SCOPUS, Web of Science, and Google Scholar databases to identify COVID-19-associated TTS case reports and evaluated patient-level demographics, clinical attributes, and outcomes. There are 12 cases reported of TTS associated with COVID-19 infection with mean age of 70.8 ± 15.2 years (range 43–87 years) with elderly (66.6% > 60 years) female (66.6%) majority. Despite a lower prevalence of cardiac comorbidities in COVID-19 patients, direct myocardial injury, inflammation, and stress may contribute to TTS with a high complication rate. However, limited data on TTS in COVID-19 patients with only a handful of case reports promoted us to systematically review the published cases and pertinent outcomes. Furthermore, a modest increase in cardiac troponin and ECG changes suggestive of myocardial injury was noted in all the cases, which is commonly seen in TTS [26] , and could mimic acute coronary syndrome (ACS).	./cache/cord-292997-xbomgwzx.txt	./txt/cord-292997-xbomgwzx.txt