id author title date pages extension mime words sentences flesch summary cache txt cord-293080-b4pxjrcj Zhang, Chunyan Establishing a high sensitivity detection method for SARS-CoV-2 IgM/IgG and developing a clinical application of this method 2020-09-18 .txt text/plain 4173 190 55 Immunological diagnosis of COVID-19 is mainly achieved through testing specific antibody IgM and IgG responses after human infection with SARS-CoV-2 and is based on antigen-antibody capturemethods. Such methods include lateral flow assays and provide the advantages of easy operation, quick test results, no need of a special laboratory site with (complex) instruments, and high sensitivity and specificity, and is suitable for carrying out large-scale SARS-CoV-2 infection/screening as point-of-care sites [7] . Based on the process of SARS-CoV-2 infection and the production of specific antibody responses, a diagnostic IgG and IgM detection assay would be the most useful method to diagnosis the occurrence of COVID-19 and development of pulmonary disease. In the present study, the recombinant protein and test strip for detecting the SARS-CoV-2 antibody by the antigen capturing method, and its preparation method were provided, supporting a new method for SARS-CoV-2 infection screening, diagnosis, disease monitoring and prognosis evaluation. ./cache/cord-293080-b4pxjrcj.txt ./txt/cord-293080-b4pxjrcj.txt