id author title date pages extension mime words sentences flesch summary cache txt cord-293500-z28bws23 Guan, Wei-jie Cardiovascular comorbidity and its impact on patients with Covid-19 2020-04-27 .txt text/plain 461 30 39 Comorbid hypertension correlates with poorer outcomes in patients with Covid-19. We truly appreciate the comments from Sisnieguez et al., who have performed a further analysis on the potential association between cardiovascular comorbidities and the clinical outcomes of Covid-19 (in particular, the mortality) [1] . We also applaud the suggestion to thoroughly adjust for the potential confounding factors when interpreting the association between specific categories of cardiovascular comorbidities (e.g., hypertension) and the clinical outcomes of Covid-19. Our findings could have also been attributed to the relatively low proportion of patients with co-existing hypertension and coronary heart disease in our study. The causes for the association between cardiovascular diseases and the poor clinical outcomes of Covid-19 might be multifaceted, including but not limited to the interaction with the age, and the cardiac dysfunction due to viral infections. Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study ./cache/cord-293500-z28bws23.txt ./txt/cord-293500-z28bws23.txt