id author title date pages extension mime words sentences flesch summary cache txt cord-293559-c78wcr8m Rego, Gabriel N. A. Current Clinical Trials Protocols and the Global Effort for Immunization against SARS-CoV-2 2020-08-25 .txt text/plain 9752 506 53 Two purified inactivated SARS-CoV-2 vaccine candidates, an mRNA-based vaccine mRNA1273, and the chimpanzee adenoviral vaccine ChAdOx1 are currently in phase III clinical trials in the respective countries Brazil, the United Arab Emirates, the USA, and the United Kingdom. Thus, during the pandemic caused by COVID-19, several vaccine candidates with attenuated virus, encoding, or presenting SARS-CoV-2 antigens have been developed globally, reaching clinical trial phases I or II for the evaluation of their safety and immunogenicity. Six protocols are developing phase II and/or III clinical trials using the chimpanzee adenoviral vector ChAdOx1 [50] [51] [52] , purified inactivated SARS-CoV-2 vaccine [53, 54] , and mRNA-1273 vaccine [55] . A Phase I Clinical Trial to Evaluate the Safety, Tolerance and Preliminary Immunogenicity of Different Doses of a SARS-CoV-2 mRNA Vaccine in Population Aged 18-59 Years and 60 Years and Above ./cache/cord-293559-c78wcr8m.txt ./txt/cord-293559-c78wcr8m.txt