id author title date pages extension mime words sentences flesch summary cache txt cord-294336-fqobpo47 Soy, Mehmet Hemophagocytic lymphohistiocytosis: a review inspired by the COVID-19 pandemic 2020-06-25 .txt text/plain 5792 279 38 This paper aims to review the pathogenesis and the clinical picture of HLH, and its severe complication, the cytokine storm, with a special emphasis on the developed classification criteria sets for rheumatologists, since COVID-19 infection has clinical symptoms resembling those of the common rheumatologic conditions and possibly triggers HLH. Hemophagocytic lymphohistiocytosis (HLH) comprises two different conditions that may be difficult to distinguish from one another: A primary form that occurs due to genetic disorders and a secondary form that is triggered by various infections, autoimmune/autoinflammatory diseases, or chemicals [1, 2] . In this review, we aim to contribute to the rheumatologists' awareness of the life-threatening rare complication of HLH, the cytokine storm, to prevent a possible misdiagnosis in the presence of the clinical and laboratory features of COVID-19 resembling or mimicking to that of an underlying or a new-onset rheumatological condition. ./cache/cord-294336-fqobpo47.txt ./txt/cord-294336-fqobpo47.txt