id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295142-5sqkdpi8	Han, Y.	The active lung microbiota landscape of COVID-19 patients	2020-08-23		.txt	text/plain	3028	199	47	The bronchoalveolar lavage fluid (BALF), containing microenvironment information on bronchioles and lung alveoli from the lower respiratory tract, is one of key sample types for characterizing the host inflammatory response and microbiota of COVID-19 patients as lung is one of main organs for the infection of SARS-CoV-2 (7, 8) . In this study, we systematically profiled the transcriptionally active microbiota landscape in BALF from COVID-19 patients and healthy individuals, identified microorganism composition in healthy individuals and COVID-19 patients, found disease-specific active microbes in the COVID-19 patient group, revealed the interaction between several bacteria or viruses and SARS-CoV-2. The diversity analysis revealed that the infection of SARS-CoV-2 probably caused a different lung microbiota composition in the COVID-19 patient group compared with the healthy group. Our study provides insight into the active microbiota in the lungs of COVID-19 patients and will contribute to the understanding of the infection mechanism of SARS-CoV-2 and the treatment of the disease and complications.	./cache/cord-295142-5sqkdpi8.txt	./txt/cord-295142-5sqkdpi8.txt