id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-296316-huyw5eo1	Suresh, Padmanaban S.	Curcumin and Coagulopathy in the COVID19 Era	2020-07-15		.txt	text/plain	629	37	35	authors: Suresh, Padmanaban S. I want to highlight further the connection between COVID-19 associated coagulopathies and how proposing curcumin will be beneficial in this context from the available literature knowledge. COVID-19 patients exhibit thrombotic complications apart from sepsis, pneumonia, respiratory failure, etc., One of the characteristic features of COVID-19 disease is the associated coagulopathy with increased circulating D-dimer concentrations. International society of thrombosis and hemostasis proposes an algorithm of measuring D-dimer, prothrombin time, platelet count and fibrinogen in all patients with COVID-19 infection [5] . Markedly raised D-dimer (maybe 3-4 fold increase) prolonged prothrombin time, platelet count (100 9 10 9 /L), fibrinogen (\ 2 g/L) are guiding parameters in the management of COVID-19 patients. Investigators have explored the antithrombotic activities of Curcumin and mitigating effect on thrombosis by modulating platelet numbers, D-dimer and plasminogen activator inhibitor -1 in mice [7] [8] [9] . D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19	./cache/cord-296316-huyw5eo1.txt	./txt/cord-296316-huyw5eo1.txt