id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-297599-y4lu8m4k	Luo, Hua	Anti-COVID-19 drug screening: Frontier concepts and core technologies	2020-10-28		.txt	text/plain	7665	373	44	This paper thoroughly summarizes interdisciplinary notions and techniques, including disease model, biochip, network pharmacology, and molecular docking technology, etc., providing a reference for researchers in the screening of drugs for COVID-19 prevention and treatment. Some researchers are currently using mice as an animal model to test drugs and vaccines and to investigate the nature of the infection of SARS-CoV-2 [49] [50] [51] . In fact, in a study led by Qin Chuan on SARS, engineered mice that could express human ACE2 protein was successfully established, leading this Chinese team pioneered the establishment of a SARS-CoV-2 infected hACE2 transgenic mouse model [54] . For example, an effective and convenient novel mouse model in evaluating in vivo protective capacity of the SARS-CoV-2 vaccines was developed through stitching the human gene for ACE2 into an adenovirus by Perlman et al.	./cache/cord-297599-y4lu8m4k.txt	./txt/cord-297599-y4lu8m4k.txt