id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-299495-1z4udo3d	Rajendram, Rajkumar	Identifying phenotypes of COVID-19, defining their pathogenesis, and targeting treatments could improve outcomes	2020-06-24		.txt	text/plain	905	57	46	Therefore, defining and targeting treatment to the specific pathologies responsible for the various phenotypes of COVID-19 pneumonia could prevent disease progression and improve outcomes. Radiological phenotype 1 and clinical Type L COVID-19 may be associated with right-to-left (RTL) shunt (Gattinoni et al., 2020a; 2020b; Rajendram et al., 2020; Robba et al., 2020) . So, the anatomical substrate for RTL shunt in patients with COVID-19 could be extrapulmonary (EPS) as well as intra-pulmonary (Rajendram et al., 2020) . Correlating the radiological features of patients with COVID-19 pneumonia with their blood gases and lung mechanics could revolutionize the approach to management. Such a paradigm shift is urgently required because many patients with COVID-19 do not improve with the standard approach to treatment of acute respiratory distress syndrome (ARDS) (Gattinoni et al., 2020a; 2020b; Rajendram et al., 2020) . Correlation of the radiological features of COVID-19 with clinical phenotypes based on blood gases, lung mechanics and shunt could redefine management.	./cache/cord-299495-1z4udo3d.txt	./txt/cord-299495-1z4udo3d.txt