id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-299869-4yjyqjpe	Wu, J.	Systemic corticosteroids show no benefit in severe and critical COVID-19 patients in Wuhan, China: A retrospective cohort study	2020-05-14		.txt	text/plain	2945	175	46	Background: Systemic corticosteroids are recommended by some treatment guidelines and used in severe and critical COVID-19 patients, though evidence supporting such use is limited. We performed multivariable Cox models, Cox model with time-varying exposure and propensity score analysis (both inverse-probability-of-treatment-weighting (IPTW) and propensity score matching (PSM)) to estimate the association of corticosteroid use with the risk of in-hospital mortality among severe and critical cases. For critical COVID-19 patients at admission, results were consistent with former analysis that corticosteroid use did not reduce in-hospital mortality. Two studies of patients with SARS and influenza A (H1N1) viral pneumonia showed that the use of systemic corticosteroids was associated with reduced mortality in critical patients [6, 8] . 11.20097709 doi: medRxiv preprint harm or benefit for the use of systemic corticosteroids in severe and critical COVID-19 patients. Corticosteroid use showed no benefit in reducing in-hospital mortality either in severe or in critical COVID-19 cases.	./cache/cord-299869-4yjyqjpe.txt	./txt/cord-299869-4yjyqjpe.txt