id author title date pages extension mime words sentences flesch summary cache txt cord-300978-busx8w6s Apetrii, Mugurel A brand-new cardiorenal syndrome in the Coronavirus Disease- 2019 (COVID-19) setting 2020-06-04 .txt text/plain 2999 151 40 Although the pandemic outbreak of coronavirus disease-2019 (COVID-19) targets preferentially patient's lungs, recent data have documented that COVID-19 causes myocarditis, acute myocardial infarction, exacerbation of heart failure and acute kidney injury. Studies show that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), similar to its predecessor SARS-CoV, engages angiotensin-converting enzyme 2 (ACE2) as the entry receptor. In patients with SARS-CoV-2 infection, the most important features that suggest myocardial injury are electrocardiogram changes and troponin elevation coupled with echocardiography showing signs of subclinical left ventricular diastolic impairment or even reduced ejection fraction (EF) in severe cases [11] , with a higher likelihood of the need for mechanical ventilation in those with reduced EF, as was seen during previous coronavirus outbreaks [9] . Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection ./cache/cord-300978-busx8w6s.txt ./txt/cord-300978-busx8w6s.txt