id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-302228-n5o6jfs2	Lodise, Thomas P.	COVID‐19: Important Therapy Considerations and Approaches in this Hour of Need	2020-05-05		.txt	text/plain	1935	113	50	A number of novel and repurposed therapies agents with activity against SARS-CoV-2 have been identified and most institutions have developed clinical pathways to operationalize their use in appropriate COVID-19 patients.1-3 However, optimal drug therapy decisions for those with moderate to severe COVID-19 infections are extremely challenging at this time as evidence is limited. A number of novel and repurposed therapies agents with activity against SARS-CoV-2 have been identified, and most institutions have developed clinical pathways to operationalize their use in appropriate COVID-19 patients. If data are amassed on COVID-19 patients, it is important that detailed information is collected on the outcomes associated with the treatment strategies used at our respective institutions. Despite data suggesting that lopinavir-ritonavir was active against SARS-CoV-2 infection, no benefit was observed with lopinavir-ritonavir treatment versus standard care in a study of hospitalized adult patients with severe COVID-19.	./cache/cord-302228-n5o6jfs2.txt	./txt/cord-302228-n5o6jfs2.txt