id author title date pages extension mime words sentences flesch summary cache txt cord-302864-2xnq1oq7 Quartuccio, Luca Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care 2020-05-15 .txt text/plain 3182 183 49 Patients were divided in two groups: 42 severe cases (TOCI) with adverse prognostic features including raised CRP and IL-6 levels, who underwent anti-cytokine treatments, mostly tocilizumab, and 69 standard of care patients (SOC). Nevertheless, robust data to predict the outcome of COVID-19 pneumonia after the hospital admission are still lacking [6] , though they are urgently needed in order to facilitate the assessment of anti-cytokine treatment efficacy in worse prognosis patient groups and not milder disease. The aim of this retrospective study was to evaluate baseline laboratory and immunological features in patients hospitalized for COVID-19 pneumonia and to explore such parameters in relationship to standard of care (SOC group) therapy versus anti-cytokine therapy, mainly tocilizumab, (TOCI group) that was mostly used either in ventilated patients in the ICU or non-invasively ventilated patients, mostly in the ward setting. ./cache/cord-302864-2xnq1oq7.txt ./txt/cord-302864-2xnq1oq7.txt