id author title date pages extension mime words sentences flesch summary cache txt cord-304798-j2tyjo1j Rapkiewicz, Amy V. Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series 2020-06-25 .txt text/plain 5320 286 40 title: Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series FINDINGS: In seven patients (four female), regardless of anticoagulation status, all autopsies demonstrated platelet-rich thrombi in the pulmonary, hepatic, renal, and cardiac microvasculature. We counted numbers of megakaryocytes in the lungs and the hearts of 7 COVID-19 cases and, for comparison, 9 cases of patients who died with ARDS of other causes, selected as a convenience sample from autopsies previously performed at the National Cancer Institute between 2017 and 2020. Previous pathology studies, identified by searching PubMed on June 7, 2020 for the terms "COVID-19 00 and "autopsy" or "histopathology", have reported findings in multiple organs, including thrombi on gross inspection, but did not use special stains to identify megakaryocytes and platelets in tissues of patients dying with COVID-19. ./cache/cord-304798-j2tyjo1j.txt ./txt/cord-304798-j2tyjo1j.txt