id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-305969-yy4f4x5i	Eng, John	Imaging Publications in the COVID-19 Pandemic: Applying New Research Results to Clinical Practice	2020-04-23		.txt	text/plain	1830	101	47	Most articles examining CT's diagnostic performance focus on its sensitivity for diagnosing COVID-19 pneumonia against the reference standard, reverse transcriptase polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (2). Since a patient's COVID-19 status is typically unknown at time of presentation, sensitivity and specificity are not the most clinically useful indicators of diagnostic test performance. In addition, assume a COVID-19 prevalence of 15%, (the approximate percentage of positive results found in RT-PCR tests being performed at Johns Hopkins Medicine hospitals at the present time). Although the preceding example was meant to be illustrative, the calculation demonstrates similar results-relatively low PPV and high NPV for CT-across plausible ranges of sensitivity, specificity, and prevalence (Fig 2) . In reality, there is probably no single "true" sensitivity, specificity, or predictive value that would apply to all clinical practice settings.	./cache/cord-305969-yy4f4x5i.txt	./txt/cord-305969-yy4f4x5i.txt