id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-307229-wjx90xki	da Silveira, Matheus Pelinski	Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature	2020-07-29		.txt	text/plain	8418	362	34	Additionally, elevations of IL-1β, IFN-γ, IP10 and MCP1 in infections by the novel coronavirus were associated with the Th1 response; however, an increase in interleukins of the T helper type 2 (Th2) profile, such as IL-4, IL-5, IL10, which suppress the inflammation, was also associated with a greater severity of COVID-19, which may demonstrate an imbalance in immune regulation and an attempt to minimize tissue inflammatory damage [35, 40] . In addition, obesity is an important factor for the development of T2DM-especially when associated with low levels of physical activity and poor physical conditioning-and as mentioned, both diseases are related to higher expression of ACE2, increasing the risk of advanced infection by SARS-CoV-2 [43] . Similarly, regular exercise practices at moderate levels favor the function of the human body's immune surveillance against pathogens, as they stimulate an exchange of white blood cells between the circulatory system and tissues, a fact that reduces morbidity and mortality from acute respiratory disease and infections viral.	./cache/cord-307229-wjx90xki.txt	./txt/cord-307229-wjx90xki.txt