id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-308114-68cgub5o	Afrin, Lawrence B.	Covid-19 Hyperinflammation and Post-Covid-19 Illness May Be Rooted in Mast Cell Activation Syndrome	2020-09-10		.txt	text/plain	3455	186	45	MCs, present in all vascularized tissues but dominantly at the environmental interfaces and in vessel walls (Akin and Metcalfe, 2004) , are activated by the SARS-Cov-2 coronavirus which causes Covid-19 infection (Kritas et al., 2020; Theoharides, 2020; Zhou et al., 2020) , leading to MC activation and resulting release of various subsets of the MC's >1000 potent multi-action mediators (Ibelgaufts, 2020) (including biogenic amines (e.g., histamine), proteases (e.g., tryptase and chymase), cytokines (e.g., interleukins and TNF-α), eicosanoids (e.g., prostaglandins and leukotrienes), heparin, and growth factors) increasingly thought to play a key role in driving the hyperinflammation of severe Covid-19 illness (Kempuraj et al., 2020; Valent et al., 2020) .	./cache/cord-308114-68cgub5o.txt	./txt/cord-308114-68cgub5o.txt