id author title date pages extension mime words sentences flesch summary cache txt cord-308476-pyje6txy Campochiaro, Corrado The conundrum of interleukin-6 blockade in COVID-19 2020-08-14 .txt text/plain 860 42 42 1 As a result, in the absence of a specific antiviral treatment for SARS-CoV-2 infection, many therapeutic efforts have focused on use of immunosuppressive drugs targeting the potential mediators of this hyperinflammatory state. 9 They obtained data from a prospective observational database used by the Hackensack Meridian Health network of 13 hospitals in New Jersey, USA, and did a retrospective study to compare outcomes in patients who received tocilizumab with those who did not. Interleukin 1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study GM-CSF blockade with mavrilimumab in severe COVID-19 pneumonia and systemic hyperinflammation: a single-centre, prospective cohort study Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study Tocilizumab in patients with severe COVID-19: a retrospective cohort study Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study ./cache/cord-308476-pyje6txy.txt ./txt/cord-308476-pyje6txy.txt