id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-308667-6jr3z9wx	Papachristodoulou, Eleni	Long-term and herd immunity against SARS-CoV-2: implications from current and past knowledge	2020-06-08		.txt	text/plain	1768	82	51	Furthermore, data from SARS-CoV suggest that the duration of immunity may not be sufficiently significant, while the immunity response against SARS-CoV-2 may not be efficiently effective in all patients, as relapses have already been reported. In conclusion, the development of an effective vaccine is an urgent necessity, as long-term natural immunity to SARS-CoV-2 may not be sufficient for the control of the current and future outbreaks. Information from follow-up studies of patients recovered from other coronaviruses may provide a background regarding the possible long-term immune response of SARS-CoV-2 infection. (2011) reported that antibody titers were undetectable in 21/23 patients at six years post-infection, while SARS-CoV antigen-specific memory B-cell response was undetectable in all 23 patients. As a consequence, the increasing number of individuals recovered from COVID-19 may not be able to provide effective herd immunity during subsequent post-pandemic waves of infection by mutant variants (Biswas et al. Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered 1 patient cohort and their implications	./cache/cord-308667-6jr3z9wx.txt	./txt/cord-308667-6jr3z9wx.txt