id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-309195-0scmephx	Blicharz, Leszek	Hand eczema ‐ a growing dermatological concern during the COVID‐19 pandemic and possible treatments	2020-05-08		.txt	text/plain	576	49	53	title: Hand eczema ‐ a growing dermatological concern during the COVID‐19 pandemic and possible treatments 3 Regardless of HE etiology, exposure to detergents and soaps, frequent hand washing (>20 times/day) and the use of occlusive gloves are all well-known risk factors of disease onset This article is protected by copyright. Topical steroids such as clobetasol propionate and mometasone furoate are usually the first-choice anti-inflammatory agents, though they may interfere with the skin barrier regeneration and thus their long-term This article is protected by copyright. 6 Lastly, systemic agents should be considered in severe cases refractory to topical treatment. Therapeutic options include short courses of systemic steroids during disease exacerbations, oral retinoids, e.g. alitretinoin, acitretin, and immunosuppressants such as methotrexate, azathioprine, and cyclosporine A. 6 Despite the lack of evidence on the increased risk of severe COVID-19 in immunocompromised patients, 7, 8 we believe that the first-line systemic treatment should involve oral retinoids followed by immunosuppressants in recalcitrant cases. Hand eczema: treatment	./cache/cord-309195-0scmephx.txt	./txt/cord-309195-0scmephx.txt