id author title date pages extension mime words sentences flesch summary cache txt cord-310561-67kp743f Shah, Akshay Systemic hypoferremia and severity of hypoxemic respiratory failure in COVID-19 2020-06-09 .txt text/plain 970 70 52 Therefore, we sought to characterise iron parameters, including serum iron, in COVID-19 intensive care unit (ICU) patients and relate these to disease severity. We retrospectively evaluated any serum iron profiles that were measured in critically ill patients with COVID-19 within 24 h of admission to the ICU, John Radcliffe Hospital, Oxford, UK, between March 31, 2020, and April 25, 2020. Our data suggest that serum iron may be a useful biomarker for identifying disease severity in COVID-19, whilst also being a potential therapeutic target. Serum iron was lower when compared with other cohorts of non-COVID-19 ICU patients reported previously, including those with sepsis [4] . Abbreviations: APACHEII Acute Physiology and Chronic Health Evaluation II, CRP C-reactive protein, ICU intensive care unit, IQR interquartile range, SD standard deviation Fig. 1 Associations between markers of iron status, lymphocyte count and severity of hypoxemia. ./cache/cord-310561-67kp743f.txt ./txt/cord-310561-67kp743f.txt