id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-313282-z5cues67	Schaefer, Inga-Marie	In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19	2020-06-19		.txt	text/plain	3975	189	41	Among five patients with acute-phase DAD (≤7 days from onset of respiratory failure), SARS-CoV-2 was detected in pulmonary pneumocytes and ciliated airway cells (N = 5), and in upper airway epithelium (N = 2). The findings suggest that SARS-CoV-2 infection of epithelial cells in lungs and airways of patients with COVID-19 who developed respiratory failure can be detected during the acute phase of lung injury and is absent in the organizing phase. The aim of this study was to examine the gross and histologic patterns of tissue injury in correlation with viral protein expression in the conducting airways and lungs at autopsy in a series of patients with confirmed SARS-CoV-2 infection. Overall, the different stages of DAD observed histologically correspond to the estimated time interval from onset of respiratory failure to death; however, the exact timing of severe lung injury may be difficult to determine in certain cases given reports of silent hypoxemia in COVID-19 infected patients [27, 28] .	./cache/cord-313282-z5cues67.txt	./txt/cord-313282-z5cues67.txt