id author title date pages extension mime words sentences flesch summary cache txt cord-314002-zm02k9bw Ayanian, Shant The association between biomarkers and clinical outcomes in novel coronavirus pneumonia in a US cohort 2020-07-17 .txt text/plain 2650 160 47 Aim: To describe the association between D-dimer, CRP, IL-6, ferritin, LDH and the clinical outcomes in a cohort of 299 novel coronavirus disease (COVID-19) patients treated on the inpatient medical service at a university hospital in the District of Columbia (DC, USA). Threshold values for all biomarkers were found to be statistically significant and independently associated with higher odds of clinical deterioration and death. Conclusion: Laboratory markers of inflammation and coagulopathy can help clinicians identify patients who are at high risk for clinical deterioration in COVID-19. Elevated levels of IL-6, D-dimer, CRP, LDH and ferritin all had an independent increased risk for the clinical outcomes assessed (ICU admission, invasive ventilatory support and death), which were statistically significant. • A retrospective cohort of COVID-19 patients were identified, their admission and peak biomarkers were extracted and the odds of adverse clinical outcomes were calculated. ./cache/cord-314002-zm02k9bw.txt ./txt/cord-314002-zm02k9bw.txt