id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-314889-lo3kkrfp	Magrini, Stefano Maria	Letter to the editor regarding “lack of supporting data make the risks of a clinical trial of radiation therapy as a treatment for COVID-19 pneumonia unacceptable”	2020-07-01		.txt	text/plain	673	38	48	title: Letter to the editor regarding "lack of supporting data make the risks of a clinical trial of radiation therapy as a treatment for COVID-19 pneumonia unacceptable" Many of us in the global radiation oncology community independently raised the possibility of using low doses of thoracic radiation therapy based upon historical data suggesting benefit in pneumonia and its ongoing use in the treatment of nonneoplastic disease [5] [6] . We agree with the authors that it is essential to conduct rigorous preclinical testing of low dose radiation therapy. With old but relevant clinical data and research suggesting anti-inflammatory effects of radiation at very low doses that may affect key inflammatory cells involved in the hyper-inflammatory host response to COVID-19 [9], we do not agree that preclinical studies are require for radiation therapy and should be treated differently than the other therapies being tested.	./cache/cord-314889-lo3kkrfp.txt	./txt/cord-314889-lo3kkrfp.txt