id author title date pages extension mime words sentences flesch summary cache txt cord-315321-kax4gqhc Laplana, M. Lack of protective effect of chloroquine derivatives on COVID-19 disease in a Spanish sample of chronically treated patients 2020-09-09 .txt text/plain 2267 135 58 title: Lack of protective effect of chloroquine derivatives on COVID-19 disease in a Spanish sample of chronically treated patients Conclusion: We did not find differences of reported COVID-19 cases between treated and untreated groups, indicating a lack of protection by regular administration of chloroquine and its derivative drugs on COVID-19 infection. Thus, our study aims to test this hypothesis by evaluating the incidence 67 of COVID-19 disease in the population according to chloroquine treatment subgroups through a 68 survey. [11] 135 Discussion 136 Our results show no differences in COVID-19 prevalence among untreated and chronically treated 137 individuals with chloroquine or derivative drugs. 139 We must note that we found a clear association between the COVID-19 disease prevalence and 140 exposure to a close family member or flatmate positive for COVID-19 in both, treated and untreated 141 subjects, that points to a lack of any protective effect on SARS-CoV-2 infection attributable to 142 chronic treatment with chloroquine or derivative drugs. ./cache/cord-315321-kax4gqhc.txt ./txt/cord-315321-kax4gqhc.txt