id author title date pages extension mime words sentences flesch summary cache txt cord-315576-bgcqkz0p Yamamoto, Naoki Apparent difference in fatalities between Central Europe and East Asia due to SARS-COV-2 and COVID-19: Four hypotheses for possible explanation 2020-08-05 .txt text/plain 6114 280 51 The comparison of the numbers of cases and deaths due to SARS-CoV-2 / COVID-19 shows that people in Central Europe are much more affected than people in East Asia where the disease originally occurred. Trying to explain this difference, this communication presents four hypotheses that propose the following reasons for the observed findings: 1) Differences in social behaviors and cultures of people in the two regions; 2) Possible outbreak of virulent viruses in Central Europe due to multiple viral infection, and the involvement of immuno-virological factors associated with it, 3) Possibility of corona resistance gene mutation occurring among East Asians as a result of long-term co-evolution of virus and host, and 4) possible involvement of hygienic factors. For the analysis of the difference regarding the number of infected people and the death tolls due to COVID-19 between Central European and East Asian 5 countries, we have chosen Italy, Spain, France, Germany and UK from Central Europe and China, South Korea, Japan, and Taiwan from South East Asia. ./cache/cord-315576-bgcqkz0p.txt ./txt/cord-315576-bgcqkz0p.txt