id author title date pages extension mime words sentences flesch summary cache txt cord-315864-zadogqiu Davido, Benjamin nImpact of medical care including anti-infective agents use on the prognosis of COVID-19 hospitalized patients over time 2020-08-02 .txt text/plain 3619 188 49 Conclusion: The present study revealed a significant decrease of admission in ICU over time probably related to multiple factors, including a better indication of pulmonary CT-scan, of oxygen therapy, and a suitable prescription of anti-infective agents. The following data were collected from patient's medical charts: -Patient characteristics: age, sex, diabetes, cardiovascular risk factors, smoking habits, obesity, chronic pulmonary disease, Charlson comorbidity index (CCI) [11] , -Infection characteristics: delay between onset of symptoms and admission, presence of super-infection, C-reactive protein (CRP) and white blood cell count (WBC) at admission, percentage of lung injuries on CT-scan if applicable, positive PCR amplifying the betacoronavirus E gene and the SARS-CoV-2 RdRp gene on nasopharyngeal swab or sputum, -Treatment characteristics: requiring ICU support with invasive ventilation and associated therapeutic strategies (e.g. oxygen, anti-infective agents), -Endpoint was defined as unfavorable outcome assessed by the requirement of a transfer in ICU for invasive ventilation and/or death within 30 days, -Patients were followed-up until hospital discharge. ./cache/cord-315864-zadogqiu.txt ./txt/cord-315864-zadogqiu.txt