id author title date pages extension mime words sentences flesch summary cache txt cord-316100-15zj660u Issitt, R. Coronavirus (COVID-19) infection in children at a specialist centre: outcome and implications of underlying high-risk comorbidities in a paediatric population 2020-05-25 .txt text/plain 4235 271 47 Given the documented reduced overall severity reported in children with COVID-19, we examined a cohort of paediatric patients presenting to a specialist children's hospital with suspected COVID-19 to document their clinical behaviour and outcomes with particular regard to presence of underlying medical conditions leading to "vulnerability". In the present study for example, for the majority of underlying conditions there was no difference between the groups, although children undergoing chemotherapy for paediatric malignancy were over-represented in the CoVPos group, suggesting these specific patients are at increased risk of Sars-Cov-2 infection. These data report on a highly preselected group of high risk paediatric patients attending a specialist children's hospital with features suggestive of COVID-19, and demonstrate that around one third of such cases represent confirmed acute infection with SARS-CoV-2. Patient demographic data, proportion in vulnerable groups and mortality of 168 CoVPos and CoVNeg patients presenting to a specialist children's hospital with symptoms suggestive of COVID-19 disease. ./cache/cord-316100-15zj660u.txt ./txt/cord-316100-15zj660u.txt