id author title date pages extension mime words sentences flesch summary cache txt cord-318044-podm4mjd Wu, P. The Trans-omics Landscape of COVID-19 2020-07-22 .txt text/plain 4681 318 52 In addition to the above abundant structural lipid classes, 314 several bioactive lipids also changed significantly in the symptomatic groups, including 315 lysophosphatidylcholine (inhibiting endotoxin-induced release of late proinflammatory cytokine) (Yan et al., 2004) and lysophosphatidyliositol (an endogenous agonist for 317 GPR55 whose activation regulates several pro-inflammatory cytokines) Cancino et al., 2017), suggesting that lipidome changes that interfere with cell 319 membrane integrity and normal functions or disturb inflammatory and immune states 320 may play important and complex roles in COVID-19 disease development ( Figure S9) . However, comprehensive analysis of multi-omics data 379 within a large cohort remains lacking, especially for patients with various severity 380 grades, i.e., asymptomatic across the course of the disease to critically ill. Performance of Machine Learning Model to Predict COVID-19 Patient 1229 Severity of Asymptomatic, Mild, Severe and Critical using Multi-omics Data ./cache/cord-318044-podm4mjd.txt ./txt/cord-318044-podm4mjd.txt