id author title date pages extension mime words sentences flesch summary cache txt cord-318355-38x3f3ee Yang, Yang Visceral Adiposity and High Intramuscular Fat Deposition Independently Predict Critical Illness in Patients with Sars‐COV‐2 2020-07-17 .txt text/plain 3963 228 48 High visceral to subcutaneous adipose tissue area ratio (VSR, called visceral adiposity) (OR: 2.47, 95CI: 1.05 to 5.98, p=0.040) and low mean attenuation of skeletal muscle (SMD, called high intramuscular fat [IMF] deposition) (OR: 11.90, 95CI: 4.50 to 36.14, p<0.001) were independent risk factors for critical illness. In the present study, we explored the relationship between abdominal adipose tissue distribution, skeletal muscle area and IMF deposition and severity of COVID-19, in a retrospective cohort of 143 patients who had an un-enhanced abdominal computed tomography (CT). In this study, visceral adiposity and high IMF deposition were significantly associated with critical illness for patients with COVID-19. The present study showed that high IMF deposition was significantly associated with risk of critical illness and requiring mechanical ventilation in patients with COVID-19. Our findings show that patients with visceral adiposity or high IMF deposition were more likely to develop into critical illness when infected with COVID-19. ./cache/cord-318355-38x3f3ee.txt ./txt/cord-318355-38x3f3ee.txt