id author title date pages extension mime words sentences flesch summary cache txt cord-318470-2plv75os Russell, Matthew R. COVID-19 in a pediatric heart transplant recipient: Emergence of Donor Specific Antibodies 2020-04-29 .txt text/plain 531 46 50 title: COVID-19 in a pediatric heart transplant recipient: Emergence of Donor Specific Antibodies Early reports have suggested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) associated coronavirus disease 2019 (COVID-19) generally causes mild disease in children. 1 Pediatric solid organ transplant recipients are generally more susceptible to viral respiratory infections and have increased morbidity and mortality. Potential for COVID-19 disease was considered but community incidence was low at the time, the patient had no Center for Disease Control risk factors for infection, and testing was not widely available. Repeat SARS-CoV-2 nasal PCR was planned for two weeks with repeat anti HLA antibody testing and IVIG administration repeated every month for two more months. 5 This patient tolerated IVIG administration with concurrent COVID-19 infection without any notable reaction. Although mechanisms and relationship between allosensitization and COVID-19 remain uncertain, we suggest careful measurement of donor specific antibodies be undertaken in heart transplant survivors of this infection. ./cache/cord-318470-2plv75os.txt ./txt/cord-318470-2plv75os.txt