id author title date pages extension mime words sentences flesch summary cache txt cord-319007-w3pk3ha1 Zingaropoli, Maria Antonella Major reduction of NKT cells in patients with severe COVID-19 pneumonia 2020-11-13 .txt text/plain 3834 194 48 Conclusions: The low percentage of NKT cells in peripheral blood of COVID-19 subjects and the independent association with the severity of the disease suggests a potential role of this subset. The increase of PMN/T ratio and the reduction in the percentages of T cells, CD3+CD8+ cells and NKT cells resulted independently associated to the severity of the disease in patients with COVID-19 pneumonia (Table 4) . To the best of our knowledge, this is the first study that characterized NK populations according to CD56 expression and that investigated NKT cells in patients with COVID-19 pneumonia correlating these subsets to clinical parameters and severity of the disease. (30) , in COVID-19 subjects we observed a significant lower percentage of NKT cells compared to HDs. We reported also the same finding in the severe group compared to the non-severe one. ./cache/cord-319007-w3pk3ha1.txt ./txt/cord-319007-w3pk3ha1.txt