id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-319273-ok2p1h9f	Lai, Yu-Ju	Severe acute respiratory syndrome coronavirus-2 and the deduction effect of angiotensin-converting enzyme 2 in pregnancy	2020-08-17		.txt	text/plain	2688	214	53	Angiotensin-converting enzyme 2 (ACE2) has transient overexpression and increased activity during pregnancy, which is now confirmed as the receptor of SARS-CoV-2 and plays essential roles in human infection and transmission. The management strategy includes monitoring fetal heart rate and uterine contractions; early oxygenation if O(2) saturation is less than 95%; empiric antibiotics for prevention of secondary infection; corticosteroid to treat maternal SARS-CoV-2 disease routinely is not suggested, only for fetal lung maturation in selected cases; and consideration of delivery is according to the obstetric indication, gestational age, and severity of the disease. 40 But a study indicated that angiotensin-converting enzyme 2 (ACE2), which is the receptor of SARS-CoV-2, was highly expressed in maternal-fetal interface cells, suggesting the possibility of vertical transmission. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes	./cache/cord-319273-ok2p1h9f.txt	./txt/cord-319273-ok2p1h9f.txt