id author title date pages extension mime words sentences flesch summary cache txt cord-319851-mhnp42xo Cao, Xiaoling Authors’ response to letter by Fogacci, Borghi and Cicero, “Misinterpreting data in lipidology in the era of COVID-19” 2020-07-09 .txt text/plain 765 48 54 Furthermore, in a longitudinal study at another hospital in Wuhan, we examined lipid profiles from inpatients (n=21) before viral infection, on admission, and during the course of their illness. 2 Collectively, this evidence demonstrates that decreases in LDL-c levels are associated with severity of COVID-19 and reflect the disease course. We are well aware of the concerns raised by Drs. Fogacci, Borghi and Cicero about the potential effects of lipid-lowing medications being given routinely to those patients with cardiovascular disorders (CVD) or diabetes on their LDL-c levels on admission. In U.S., Italy and other nations, as many as half or more of patients with CVD or diabetes would be taking statins prior to onset of COVID-19 and many of them would continue until the time of hospital admission. 3, 4 Therefore, hypolipidemia in COVID-19 patients most likely results from SARS-CoV-2 infection and associated hyper-inflammation, not lipid-lowering medications. ./cache/cord-319851-mhnp42xo.txt ./txt/cord-319851-mhnp42xo.txt