id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320149-3q4q98a6	Di Carlo, Davide Tiziano	Exploring the clinical association between neurological symptoms and COVID-19 pandemic outbreak: a systematic review of current literature	2020-08-01		.txt	text/plain	3482	196	39	An increasing body of evidence suggests that patients with the coronavirus disease (COVID-19) might have a heterogeneous spectrum of neurological symptoms METHODS: A systematic search of two databases was performed for studies published up to May 29th, 2020. The pathophysiology of this association is under investigation and warrants additional studies, Physicians should be aware of this possible association because during the epidemic period of COVID-19, early recognition of neurologic manifestations otherwise not explained would raise the suspect of acute respiratory syndrome coronavirus 2 infection. Our systematic review of 2499 patients reported the occurrence of a wide spectrum of neurologic complications in hospitalized patients with laboratory-confirmed COVID-19 infection, supporting the possible neuroinvasive potential of SARS-CoV-2. Recently, several case reports described the occurrence of ischemic and hemorrhagic stroke (see supplementary material 1), confirming the association of cerebrovascular complications with severe COVID-19 infection, older age, and the presence of multiple comorbidity [46, 47] .	./cache/cord-320149-3q4q98a6.txt	./txt/cord-320149-3q4q98a6.txt